I've always had excellent results with Red Dot in 45 Colt, loading around 6.0-6.1 grains with 250-255 g cast bullets. Since starting to load for handgun/rifle back in '76, I've never chronographed a single round. Mostly I guess because I've never had one available or bothered to buy one. Always went off what the fps would be by previously published reports. As long as the bullet did what it was suppose to do (hit the target or kill the game), that did it for me. Not to say having a chrony' isn't needed or desirable, but for CAS shooting, losing 51 fps and if your hitting the metal, what the heck. As also posted, the guns used by the 'lab' boys are a lot different than what you and I shoot. I always look at what they established their results with and subtract some fps for barrel length or take into consideration if they are using a so-called test barrel. Ya gotta use the reports as a guide, not the ultimate conclusion. Red Dot is a 'goody'-I plan on keep on using it.