Anything's possible, but I have never heard of the 1868 Navy barrels being rechambered for the Spencer cartridge or used on French (or any other nation's) rolling blocks. However, I have heard of rolling blocks chambered for a Spencer cartridge. And I suspect Spencer cartridges would fit in the Navy chamber without alteration, so it would be merely a matter of swapping in a rimfire breechblock.
A sidenote: I recently read about a Canadian militia practice of which I was unaware: in order to simplify ammo supply in the 1860's-70's timeframe they reportedly used Spencer ammo (would have been .56-.52 or .56-.50, for the 1865 models) in both their Spencers and their Peabody rifles. Both the Spencer and Peabody cartridges were rimfires, and both nominally .50 caliber, but the Peabody cartridge was significantly longer and held 50% more powder than the Spencer. Kind of a precursor to shooting .38 Special in a .357 Mag, although on a much larger scale. The Canadians also apparently complained to the Providence Tool Company (manufacturer of the Peabody) about the inaccuracy of the Peabody rifles when used with Spencer ammo, which was, of course, not the ammo intended for use in their Peabodys.