Hello Doc
Your question really needs to be answered my you, it's all about what feels good to you not some other pard, I have large hands, and put Gun Fighter Grips from Eagle Grips on my New Model Ruger Vaquero's, and that gave me exactly what was right for me, if you say you have small hands, the Gun Fighter grips might work well for you too, they seem to have a big following by both by pards with large and small hands, I found the smoke wagon to have average size grips on them, but with checkering, I shoot 45 long colt, and prefer a smooth grip, if I were to carry my gun in cold or wet weather, the checkered grips would be my choice, but for CAS, smooth works better for me.
Regards
tEN wOLVES