Well, I don't personally have any Colt handguns, but the Richards-Mason Open-Top kinda take my fancy. I like the grips on the Navy, but you would have to see for your self. Feel for yourself. As for rifles, the Winchester 1873 chambered in 45 Long Colt or in 44-40 Winchester was used for deer hunting from the time it was invented into modern times. The Sharps works equally well in any of it's chamberings, and has plenty of killing power out to around 800(?)yds.
If you want to span fifty years you could use my personal arsenal. I have a 44 caliber Remington New model Army revolver and a Winchester model 1894 in 30 W.C.F.
Just some information for ya'.
Have fun.
--TK