I have both styles on my guns. I have mostly checkered grips on all of my cowboy guns except for my Cimarron .45Colt, my two .22 single action Rugers (super single six and the Bearcat), and the Beretta Stampede I'm having grips made for as I type this, those are being made out of Ziricote from "Outlaw Grips".
I haven't shot enough recently to be able to inform you if I have a preference or not.
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