Howdy DWC, the 44/40 is the best rifle caliber IMHO for the obvious reasons. They seal the chamber and feed smoother, so there is never an issue with blow back or fouling, especially when shooting BP. I've yet to have a problem reloading with Hornady One Shot case lube, a little shot is all it takes. Plus the 44/40 is an original rifle cartridge. Good Luck.
Jefro