I have a bunch of the Lyman #2. The Marbles has the added feature of a windage adjustment. Generally for up to 100 yards I have never had to make a windage adjustment after the sights are well settled in. If wind is a problem in your area, I'd opt for the marbles. I use a windage adjustible sight on my Browning 86 SRC and have fired it out to over 400 yards with good effect.
For firearms with a dovetail front sight use a drift to set the windage at the front. Once the windage is set, use the rear screw adjustment for elevation. I found that a 75 yard zero keeps the bullet within a couple of inches of the sight line most of the way, but down a bit at 100, but manageable.
My Uberti 1866 carbine has a fixed foresight. The Marbles weren't available then, so I made shims from pistol brass. The case walls are tapered so a slice sawed off of a .38 Spl case gives a modest taper, and 9mm cases give a bit steeper taper. Flatten the slice & drill it out for the sight mounting screws and slip them between the sight and the tang & orient them to tip the sight staff in the desire direction to correct windage. A bit of a fuss, but it worked.
Like for many other questions, the answer is "it depends!"