I know Rugers are tough, I love my Rugers, but people hot rod the 45 colt to 44 mag power levels and it's not wise, there are warnings about it because of the thinner case. Doing this to a 44wcf would be even worse. It just doesn't make sense today when guns are available for more powerful calibers.
Your better to buy a 44 mag and if someone wants to hot rod a 45 colt buy a 454. If you want more you can get a 460, 500, and there's always the 475 and 480 in there.
Why risk injury or your gun by running something dangerous through it?