SL,
Use Bore Butter and do some of the tricks mentioned for BP '58 Remingtons. Chamfer the cylinder pin hole on the cylinder, ,pack the pin as full of Bore Butter that you can. you might go as far as lubing over the chambers with bore butter like a C & B cylinder is done to prevent chain fires.
Easier way is to outside lube your bullets with Bore Butter this will help a lot.
The bore butter works! I shot 5 stages Sunday with a "58 Pietta RemC & B and a '58 Pietta Rem Kirst 44 Rem Conversion. the C & B performed flawlessly and so did the 3 cylinders I switched out. The Conversion ran smooth up to the last stage then was a little stiff only when i unloaded at the unloading station after the last stage. I use outside lubed 44 Rem. that I load. I lube with Bore butter. and the conversion uses BP.
On the C & B I packed the cylinder pin as full of bore butter as I could, lubed the pawl (star on the back of the cylinder) and stuffed bore butter into the cylinder pin hole, lubed over the balls to prevent chain fire and my Pietta "58 rocked.
Also I almost forgot, I use NO petroleum based lubricants at all None Zip Nada, I use Olive Oil for the internals and all other lubing on the pistols. I clean with hot soapy water dry then use the olive oil.