A full reline is not necessary as bore size is the same for both .44 Special and .44-40. However, Coffinmaker is correct about the chamber sleeve. There is a vast difference between these two cartridges, so the chamber must be sleeved and then reamed with a .44 Special chamber reamer. I'm not sure why the carrier would need any modification, unless the carriers in the later guns has changed. I say this because I have one of the first Uberti Henrys ever imported into this country. Caliber is .44-40, serial number is 1826 and it was sold through Allen Firearms in Santa Fe, back in the early to mid 80's. Factory .44 Special ammo with feed through the tube and carrier without a hitch, I just can't chamber them. I would think that any gunsmith who works on old vintage firearms could and would sleeve the chamber on your Henry.