Up to now my wife has been shooting 6 grs Red Dot in her Pietta 44-40 SAAs with 200 RNFPs 'cause that's what I load for my 44-40 rifles.
It's a tad much for her so on a recommendation I tried 5 grs of Tite Group. It's supposed to be conducive to large capacity cases. She and her guns like it and she groups better with them than with any other calibre or load. No flinching or pulling trying to beat recoil.
I've recently acquired a pair of Pietta 44-40s myself and I think I'll use it as well.
The Piettas are proving to be the best timed, best fitted, best looking CAS revolvers we've ever owned! We're both shooting 7-1/2" barrels, her frames blued, mine case coloured with poly-ivory grips.