My 1866 Carbine was purchased used.....the prior owner installed the very rear sight, per Mr. Ketchum's earlier posting. I find it works well on the Carbine out to 75-100 yds.
My 1866 Rifle has the factory ladder sight. It will stay in place pretty well when it is elevated for use. At least it doesn't drop or slide around during firing. Mine is 44-40 and I shoot 30 grains FF & 200 grain "Big-Lube" slug. I have shot it out to 400+ yds on a rather generous steel target while at the NCOWS National shoot some year back. We did not know the range, but guessed 400 & slide the ladder sight to the 400 mark (alignment as best possible). I fired a few shots, spotter (Badlands Bruce) said "low", I elevated a smidge and fired with several hits following. The NCOWS judge was present and asked about the distance and he said 420-something yds he had lased the targets earlier). Moral of the story, The buckhorn will work fine out to nearly 100 yds and perhaps to 200 yds (if you have adjustable elevation). If you have interest to toy with shooting 200+ yds, replicating Henry Cartridge ballistics (particularly with 44-40 BP loadings), and a period correct (1860s) sight, the ladder is my choice.
If it would not stay in place, I'd go with Coffinmaker's suggestion to drill/tap a hole for a thumbscrew. If I need another project someday, I'll do this and add an oversize thumbscrew with my install.
Best,
Slim