Froogal 

45 Colt "what"    Pistol??  Rifle??  1911??  10 Pounder field Piece??

So, with Black Powder you're gonna get fouling to some extent regardless.  Black Powder fouling is cumulative.  Builds up a little every shot.  Doesn't matter what cartridge you use.  It does matter the "quality" of yer powder.  The other prime consideration is to keep the fouling soft.  Hence, we like lotza lube.

Cartridges:  45 Colt and other straight wall cartridges will foul the chamber and in many cases the action from "Blow-By" of gun gasses.  Icky Foo, unless precautions are taken.  Blow-By can be eliminated by annealing cases.  You can also eliminate blow-by in 45 Colt by fire forming 44-40 cases to 45s.  Unfortunately, there is no other case choice for the other straight wall cases.  Anneal them.

Annealed cases will not affect the fouling lift in the bore.  Only keeps the chamber and the action components clean, free running and sanitary.

Last Choice.  Switch.  Switch to APP.  APP requires no lube and the bore fouling is not cumulative.  Each shot cleans out the previous.  APP can and will foul the chamber and action though, if enough Blow-By is present.  Annealing and or 44-40 fire form'd will probably be required.

Wife and I have a pair of those Rossi's. Hers is 38/.357 and mine is .45 Colt. The safety thing on hers seemed to become activated all by itself and then the rifle would not fire when she wanted. I neutered the darn thing. It looks like it is still there, but it cannot be activated.

Morning y'all.
Coffee and tea are ready.

"Tis 45 and sunny. "Breezy. Warmer. Mostly sunny. A slight chance of showers and thunderstorms in the afternoon. Highs in the lower 80s. Southwest wind 10 to 15 mph increasing to 15 to 25 mph in the afternoon. Chance of rain 20 percent."

Slim

Johnson Barr
I sent you a message in reference to your Accurate Mold.
Macon Due 29445

Have used it for a number of years now. Fill to the base of the bullet with no more than light compression, and it will deliver consistant velocity and minimal, nom cumulative fouling. Velocity will be close to the standard spec for the caliber. Or a .38 spl 150 grainer will be around 800 fps. Standard primers and moderate crimp. Clean with plain water and oil as normal. Cases dropped in plain water will be clean and ready to load after drying.  You will need to use bp lubed bullets for best results.