Having both a S&W (old) and a Uberti, I have to say no. I haven't tried to fit the old grips on the Uberti, but I did try to fit the Uberti grips to the S&W, no go. Also got ahold of some old ASM Schofield grips, again no go on the S&W. They could probably be made to work if I wanted to put a little more effort into it, but it was just an experiment I was able to do cheaply. Most of the ;extra; grips you will find out on the market today will be made for the Uberti frame.