I have used separate fireforming loads, but only when I need to blow out a tapered neck, like .30-30 to .38-55 or .30-40 Krag to .375 Flanged Nitro Express. If the purpose is to effect a fairly minor change, why waste the primers, powder and time spent stuffing wadding over the powder?
I load for my Brno 304 7 x57R combination gun. I have RWS cases for full bore loads, but like to have cast bullet small game loads in my pocket. For these I use .303 Brit cases. I run them through a 7 X57 die to bring the neck to size and load them. They are a bit skinny for the first shot but blow out considerably upon firing. The next reload is with a fully formed case. Either way, the results are exactly the same.