With a single shot rifle, where cartridge length might not be an issue, you can leave a grease groove or two out of the case. This allows for more powder.
With a lever action in 45-70, and feeding from the magazine, you don't have this option. Getting 70g of BP into a 45-70 and maintaining SAMMI length with 500+g bullets is a real trick.
Some BP does not like lots of compression for best accuracy. With 500-535g bullet, and even with leaving a grease grove out of the case, I have a hard time getting 65g of BP with good accuracy. With Goex powder, if I compress too much, accuracy goes out the window. With Swiss and Schutzen, I can compress much more and maintain accuracy.
I drop all powder through a 24" drop tube.
In my 38-55 I've been using 3F to get the velocity with 340g bullets that I need for 300 yds. I've not tried 3F in the 45-70 yet.
Have others used 3F in the 45-70?