I use Unique powder in my .45 acp because it works well with the 230 grain cast bullets that I prefer and because it works well in most standard pressure, large bore revolver/pistol cartridges such as the .44-40, .45 Colt, etc. It allows me to stock up on a single powder that performs well in revolver, and even rifle reloads with cast bullets. Using it in cast bullet, practice loads for .45-70, 9.3x62, .32 Special, etc allows for a lot of fun practice for low cost. I see that many people seem to use Trailboss for similar purposes now but I have never switched from good old Unique. Soot safe.